Thursday, June 03, 2010
One of every five persons aged 65 years is predicted to develop Alzheimer’s Disease (AD) in their lifetime. The apparent substantial heritability of late-onset AD is inadequately explained by genetic variation within the well-replicated genes.
Netherlands Consortium for Healthy Ageing researcher Monique Breteler (Erasmus Medical Centre) reported genome-wide significance for two loci related to AD on chromosome 2 and 19, that appear to be independent of the gene apolipoprotein E, which is well established to be associated with AD.
Read more