Wednesday, December 15, 2010
Researcher Hermen Overkleeft from the Netherlands Proteomics Centre (NPC) together with his colleagues of Leiden University and the AMC developed a method to visualise the enzyme GBA1 in living tissue. Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal storage disorder. As a treatment, the enzyme is administered to patients suffering from this disease.
The new visualisation method can lead to better diagnostics and in the long run to a more effective treatment.The researchers published their method in Nature Chemistry & Biology.
read more